Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R
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چکیده
منابع مشابه
Role of IL‐18 in atopic asthma is determined by balance of IL‐18/IL‐18BP/IL‐18R
It is recognized that IL-18 is related to development of asthma, but role of IL-18 in asthma remains controversial and confusing. This is largely due to lack of information on expression of IL-18 binding protein (BP) and IL-18 receptor (R) in asthma. In this study, we found that plasma levels of IL-18 and IL-18BP were elevated in asthma. The ratio between plasma concentrations of IL-18 and IL-1...
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Interleukin- (IL-) 18 and tryptase were previously reported to relate to asthma, but the correlation between these two potent proinflammatory molecules in asthma and their roles in mast cell accumulation remain uninvestigated. Using flow cytometric analysis technique and ovalbumin- (OVA-) sensitized mouse model, it was found that IL-18 and tryptase levels in the plasma of moderate and severe as...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2017
ISSN: 1582-1838
DOI: 10.1111/jcmm.13323